Possibly sick??

My daughter is a very good baby, she just turned 3 months. Yesterday, out of no where she was fussy all day long and didn't get any good naps until we took a 2 hour car ride since we had to pick up a friend. Went to dinner with a bunch of friends and when she woke up, she was completely fine at first. But after 10-15 minutes, she got super fussy again and would not stop crying. I ended up having to walk back to the car and stay there, I didn't even get a bite of my food. Well, it's been happening again today where she's been super fussy and crying, could she possibly be sick? She's NEVER like this and I'm barely getting any rest during the day. I don't have a thermometer to take her temp