Just a feeling?

I know what I'm about to say will sound crazy I just need a second opinion. I've been dating this guy for three months and we have been so happy together. This past weekend we had hung out Thursday and Friday and it was fine (a tad off but he's recovering from intense mono). We spoke very shortly on Saturday and Sunday but I intiated both times. And I haven't heard from him today. It's just so unlike him. I just have this overwhelming feeling something is wrong, like he's lost interest. Like you know that feeling in your gut something isn't right. What should I do?