Wondering when to take a test

Have been trying to conceive for a 14 months now and my cycles have varied from 40-53 days. I  ovulated on October 27th and if my cycle is 41 days then I should get AF today. Nothing has come. Should I wait to test till next weekend or could I now? I mean I know I can now I just don't want to get upset if I get a false negative. Thanks!