Reflux and formula feeding?

mi
My sister had her baby girl the day before me and her LO has reflux confirmed by her doctor. They put her on enfamil AR, it made no difference. Then Galvason, still no relief. Then they said she had colic, so they put her onto inforcol drops. Now they are talking about Losec. My poor niece isn't even 8 weeks old yet and the poor baby is just screaming in pain. Has any of you mommies got any experience or advice? My poor sister is driving her self crazy. All the while the poor baby is in pain.