I'm on day 20 on the depo shot. And my body has some changes that I am not used too. I have a lot of cramping in the middle of the night and throughout the day. I'm extremely tired at times. I get very agitated and annoyed by my husband which I love but I get annoyed easily. Plus my sex drive is so down it crosses my mind to want to do something with my husband and but the thought makes me tired and then I just don't want to do anything. Am I buggin? I know I have some of the symptoms but how are there reacting to this birth control?