Suddenly refusing a bottle

My lo is breastfed and gets a bottle every night as part of her bedtime routine. The past week she suddenly started refusing a bottle, she starts screaming and crying when it's near her. I'm worried because I take night classes and my so is the one that feeds her and puts her to bed, but since she's refusing a bottle she doesn't eat from 5 pm to around 930 when I get home to nurse her. Also we booked a mini vacation on nye so she will be staying with my mom for two nights. Has this happened to anybody? Advice please!