Hey ladies, obviously Ibuprofen is a godsend for cramps, and it's gotten to the point where I take 4 pills like twice a day lol (bad, I know) but my mom is a nephrologist and has had several young women come in with kidney problems from taking too much  Ibuprofen. You can stay safe by drinking a LOT of water and staying super hydrated when you take it! Just something to keep in mind:)