Does letrozole affect OPK's

Ruth • 38, ttc #2
Hi ladies
I am on first cycle using Femera Letrozole 
I got a positive OPK on day 15 (I normally ovulate much later). I didn't, however, get sensitive nipples like I notmally do post ovulation (normally a day or two after positive OPK).
So, was wondering if the drugs can give false readings?
Or it may be the drugs have altered hormones and the normal sore nipples just didn't happen! Been ttc for 2 years during which I haven't ovulated for 4 different months. 
I have mild PCOS apparently
Waiting for results of my day 21 blood test so guess that will show if I def did ovulate but wondered if any of you had experienced false OPK readings?
Thanks xxx