Anyone have their withdrawal symptoms come back after being gone for months?

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This is only my 2nd month getting a +OPK. No depo symptoms since January... No symptoms after my +OPK in February... According to this +OPK I should have ovulated this past Sat, Mar 21st... and since Sunday my boobs have been soooo sore. I've never had this as a normal after ovulation or PMS symptom before, and I'm dreading it's still due to depo?? 😤