Hard pregnancies

Are pregnancies with girls typical harder in the first trimester? The person that I am talking about has two kids who are 3 and 1 and they are both boys. She had normal and easy pregnancies with both of them and a miscarriage in between them. She found out that she is 8 weeks pregnant and she is having sickness and dizziness and fatigue and depression. Are all these signs that could point to a girl, or is it just because of her having two kids already?