Can someone never reach an orgsam?

Is it possible for someone to not have a climax after a certain period of time in a relationship? I mean after 6-7 months of sex and orgasm, suddenly she stop reaching it. Without the love being faded away, with the same heat as before.

Update: No! I mean the love and passion an heat are still the same, even more, and so is the intimacy. Just the orgasm seems to be impossible.

Can anti-anxiety medicine also be a reason?