Scared of meds


So I have gad panic disorder and depression. Lately my depression has been getting a lot worse and too much to handle. My doctor prescribed me Zoloft about a month and a half ago, and I have a meeting with her on Thursday. I’m scared that she will be mad at me about not taking my meds right away. I’m just too scared to take them, this happened with my other pills at first too. I just took my first one tonight because I just can’t stand my depression anymore. Is it weird that I am scared to take my medicine? And should I stop smoking weed? I have my medical card and I know the last anxiety/antidepressant had not to use marijuana with the pill on the bottle. My doctor knows I smoke