I need some mommy advice

I have never once missed a period more then a day or 2. I am 5 days late! My husband and I have been trying for over a year with no luck but now I am 5 days late and we are getting hopeful. The only issue I have is the tests keep coming up negative! I was told that some tests dont work for some people what are your opinions! I am using the first response 6days sooner but I haven't had any positive results! Please help me with some hopefully helpful and good news!