Best friend needs help

So me and my best friend tell each other everything because we think we might be able to help each others situation but I'm stuck and I need some help. My best friend has lost her virginity and is no longer with that guy and is with another and they both want to take their relationship to the next level, however she is concerned and worried because her boyfriend isn't circumsized and she doesn't really know how to please him or do it without hurting him and she doesn't know if it's different from having sex with a circumsized guy.

Any help that I could give her?