Dog anxiety

Let me preface by saying he’s going to the vet on Friday. He’s a 200lbs English mastiff. We rescued him so we’re not sure of his age. Probably around 5 years old.

For the past 24 hours he’s been panting, drooling, being extra clingy and whiny. I’m thinking it’s just anxiety. He’s eating and drinking pretty normally, maybe a little less than usual, but probably because he won’t leave us alone. He’s pooping (looks normal) and peeing normally. He was running around chasing our other dog normally, he’s rolling around wanting belly rubs etc. He’s letting the other dog try to hump him and lick all over his face. I’m just concerned with his sudden clinginess/whining. My husband and I started back working full time in July after being at home/working part time for over a year due to Covid. He hasn’t been handling that too great. He’s had a few accidents in the house due to thunderstorms and near by construction. Any one have any experience with their dogs acting the same way? How can you tell a dog is sick vs anxiety? I know I’ll be an anxious mess until he goes to the vet.