FTM here... Need opinions on strollers

Krischelle • Finally pregnant after trying for 9 years! Baby's expected due date: 4/13/2016, five days after our 10 year anniversary!
I'm a first-time mom and I'm wondering if there is a huge difference in 3-wheeled strollers vs 4-wheeled ones? Is one more maneuverable than the other? Is one safer than the other? Or is it all just preference? 
Thank you for any feedback! 
xoxo