Okay this month marks my second round of trying to conceive with letrozole this month I'm also trying a metformin 500 milligrams 2 times a day also went up my letrozole to 5.0 instead of 2.5 last month I reacted to the 2.5 but I just did not release an egg so hopefully since we went up on the dosage it will actually push a mature follicle out...wish me luck....any body taking letrozole??? How is it working for yu