Depression

So I was off my anti depressants for 2 years when I moved in with my current roommate. Recently I've been upset and crying every night and sleeping all the time, so a couple of weeks ago I started taking them again but it's not helping. I feel like a jerk, and a burden to him. He's amazing g about it but I know I know he's upset. What can I do?  
Update: they are new(ish) meds