So my husband and I are trying to conceive and I find it very hard to stay positive. I am currently taking metformin (1000mg) a day and it making me feel miserable. I get severe diarrhea and my stomach always feels uneasy. I just keep taking it and try not to think about how sick I feel to my stomach. On my next cycle I will start taking letrozole and metformin.  I guess it just feels like I'm working overtime and fighting the sickness only to feel disappointed when my period comes. What does everybody else do to help the side affects of metformin and to keep from feeling so let down?