has anyone ever...

Has anyone ever taken progesterone or glutathione? I've just started taking both and getting glutathione injections each month. Long story short, I'm basically missing the gene in my body that's supposed to detox bad hormones, heavy metals, and toxic stuff. And because of it, have next to no good estrogen, but I'm too young to take estrogen. So I'm going the natural route and trying to kickstart my body into making the proper hormones and detoxing all the bad stuff from my body. 
Anyone ever taken those or gone through this? I could use some advice and support.