A study, released in May 2013 compared a well-known natural therapeutic with Clomid. In this study, 100 Egyptian women with PCOS were split into two groups. The women would receive either Clomid, or a compound made from Cimicifuga racemosa, more commonly known as Black Cohosh. The fifty women assigned to the Clomid group received the drug for 5 days, as is often the case in clinical <a href="https://glowing.com/glow-fertility-program">fertility treatment</a>. The other fifty women received a dose of Black Cohosh for 10 days.

The results were impressive. The Black Cohosh group showed significant improvements in key gonadotropin markers such as LH and LH/FSH ratios. Not only that, but the Black Cohosh group had better progesterone levels, indicating stronger, healthier ovulation and greater chances of implantation.

The endometrial lining was significantly thicker in the Black Cohosh group, which makes sense considering that Clomid thins the endometrial lining for many women.   Although it did not reach clinical significance, the pregnancy rate was also higher in the patients who received Black Cohosh, when compared to those who received Clomid.