AF didn't show

So ladies AF was supposed to show Fri took a test&negative on fri. I will probably retake on mon or something due to my irregular periods. It's just weird because I haven't missed a period in a while but i was also on vitex last month (no off of it) and my gyno just put me on Metformin last week. Have any of ypu ladies had this happen with either vitex or metformin?my doc said it would help me ovulate and reg periods but i missed it praying for baby TTC10 months😏