5 month old constant screaming

He was sick the last couple days and I had given him Tylenol and the nasal spray the doctor gave me, his fever went away. He’s been VERY upset, he used to crawl all over the floor but whenever I put him down he screams, he never wants up usually but now that’s all he wants, and he acts tired a lot (rubbing eyes, fussy) but he fights it so much, and once he does sleep he wakes up 10-20 minutes later and is fussy again

Anyone have tips or ideas to help me