I have been on Clomid for 5 months now. Last month they raised my dosage to 100 mg. I had negative OPK's all throughout that cycle (have never had a positive), but when I went for my day 21 progesterone test, my levels were at a 43! This cycle I am in 100 mg again. I am on CD16 and still haven't gotten a positive OPK this month. I use Clearblue Digital (not advanced) and do it in the morning as the instructions say that is ok. I guess my question is, can progesterone be high and you still not ovulate or am I somehow missing my surge? I should mention that I dontlike to take afternoon OPk's because I drink a lot of water throughout the day. Does anybody have any insight?