Toxic people

How do you remove toxic people from your life? What if they are relatives? I’m in such a difficult situation. Went through 2 break ups last year and now other people are still trying to bring me down. It’s worse when they are related to you and claim that they only want the best and worry about you. If that’s the case why is the conversation always so negative and why do I feel so drained and down every time they talk? Any advice would be great.