what meds can I take during ovulation day?

Thea • Married. Baby U 10.2018 mmc 👼 Eleanor Jane: born sleeping 1.16.20 at 20w5d gestation 👼 CMV awareness 🎗️ Infertility and PCOS warrior 💕

Im on cycle 3 of femera and got a positive opk today at 5pm. I am already starting to get a mild migraine and nausea. Last cycle, I ovulated and got really sick from ovulation... but I wasnt working at the time so I pushed through the day. But now I am working so what type of medications are SAFE during ovulation day? I dont want to mess anything up.