How do you stay sane when you have a crazy amount of fertility drugs in you? I'm on round 4 of letrozole (Famara), this is the first month with progesterone added. I feel like I'm on edge all day every day. Worse than when I was actually pregnant several years ago. It wasn't too bad just on the letrozole but adding the progesterone the little mood swings have gotten more often and bigger. I just don't get how some women stay on them for a long period of time without going a little crazy..