Baby sometimes DOESN'T want to be held???

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Hes 7 weeks. Hes been extra fussy randomly because he's constipated, but we are fixing that :) I keep checking his temp because of all the fussiness but it's still just 97.6 under arm. So I think it's a growth spurt or colic. Anyway, i try to hold him when hes crying and screaming but he hates it! Then when I lay him down by himself hes happy and smiley lol eventually he let's me hold him and feed him and he sleeps. This is usually in the evenings but today happened in the middle of the day. What is happening? Is the growth spurt making him extra weird for a while? Lol. I'm kind of worried but the dr didnt seem to be when I called because hes fine fever wise etc