So, I've been on Metformin for almost six months due to PCOS and my husband and I are trying to get pregnant. My period has been very regular with this medicine. This month I am 5 days late. With the PCOS when is the best time to take a test? I have no signs of my period starting and have been nauseous. The last pregnancy I had was unexpected and it wasn't until 2 weeks after my missed period that I tested positive, but that ended in miscarriage... what should I do?