Traveling with cats

I’m moving in a few months and I’m renting a uhaul and I have 2 cats. I’ve never traveled with them in the car unless it’s for the vets office. Is there any advice on what I can do to make it easy for them? I’m obviously going to keep them up front with me. But should I put them in the same carrier? I have one bigger one that I use to take them to the vet in. Or 2 separate smaller ones? I just want to make it as stress free as I possibly can for them