Tax Related / Non-resident Spouse

I’m really bad at taxes and haven’t gotten the chance to talk with a tax preparer, yet.

But... plz help a girl out... I need a little background knowledge, :)

I know I need to update my marital status. For work related, I know I will have to update my W4. Will I have to filed: Married, File Separately because my spouse doesn’t have a SSN or ITIN?

Spouse cannot work but we’ve already filled and filed for AOS and are waiting for the receipt notices.