Immunological treatment

Polly

Hoping there might be people on here who have had any kind of similar diagnosis! I live in HK but am originally from the U.K. I decided to do <a href="https://glowing.com/glow-fertility-program">IVF</a> in the U.K. as is less than 50% of the cost of <a href="https://glowing.com/glow-fertility-program">ivf</a> here in Hong Kong. After my egg retrieval I had 9 good quality 5 day blasts. Fresh transfer nothing happened. Next FET resulted in pregnancy but ended in a miscarriage at 8.5 weeks.

Next FET BFN. All single embryo transfers. Just had 4th transfer 9 days ago and have Beta test tomorrow (🤞).

Before this last one I had a full immunological panel which came back that I have a blood clotting disorder, high levels of natural killer cells and high levels of T cells. My doc here described it that my son (3.5 years old- natural conception) was like my bodies first vaccination….but now it sees it as foreign matter to expel.

The conundrum I have is that the Hk protocol for this is totally different to the U.K. here I have been put on Clexane (blood thinner injection), steroids, plaquenil, hemara and intralipid infusion x 2 (which cost an additional 5k gbp just for the drugs for this FET)

The UK told me they don’t support most of that and suggested I do Clexane and aspirin.

My doc told me here that the U.K. is very conservative, as is the public system here, so she secretly treats public patients here but when they get pregnant the docs in the public system say ‘see this immunological stuff is rubbish’. The point she is making is she truly believe it is really valuable and can help people but there are not enough conclusive studies.

So I got a third opinion from the top immunological doc in the U.K. and he was more in line with HK but still a hard no on the steroids (not because of it not potentially helping but because of the side effects etc)

Anyway it is very hard to see the woods from the trees with so much conflicting info so would just

Love to know if anyone else has experienced the immunological side of things?