Extremely unhappy toddler

I have a 5 yr old little boy and an 18 month old baby girl. My 5 yr old is the sweetest little guys he’s happy all the time and when he does throw a fit it’s usually resolved within 5 minutes of it starting. My 18 month old on the other hand she just screams all of the time, she’s so angry I don’t know what I’m doing wrong. She literally hates anyone but me and her brother so that means no one else can help her with anything because if they try she will start screaming and hitting them and me. I don’t know what to do I’m at a loss. It’s so frustrating and also heartbreaking because why is she so miserable when all anyone ever tries to do is love her and help her work through her meltdowns. Her doctor says it’s normal behavior but I don’t think so because I’ve never met a toddler who is angry absolutely all of the time. Any suggestions on why or anything I should try to help her would be greatly appreciated .