Zofran not helping

I am almost 9 weeks w my 2nd. My constant nauseous and running to the bathroom is taking a toll on me. I've been taking Zofran for the past two weeks. Some days I feel like it helps, other days (like today) I'm just plain miserable. Anyone else experiencing semi success with Zofran? I'm sort of losing it trying to care for my two year old feeling this horrid. Any other tips from moms coping with bad morning sickness (all day sickness)?