TTC with MTHFR and Factor V Leiden !?!

Question

Morning ladies -

After 2 miscarriages, we found out through genetic testing that I am heterozygous for MTHFR and Factor V Leiden. I am SO thrilled to have an answer after worrying that the miscarriages were because of something I did (working out!). I started taking Women's One a Day prenatals, and my L-methylfolate prescription - basically mega doses of folate and B vitamins - will be ready soon. I learned I'll have to be on daily self-administered injections of Lovenox and oral baby aspirin the day we find out we're preggo again.

Looking for anyone in the same or similar boat as me! Experiences and advice, suggestions, anything. Thanks 💜

Answer

I have a different clotting disorder but also have to be on Lovenox throughout pregnancy. Didn't have any issues TTC, but discovered the disorder after I gave birth to my son still born. Since then, I've had a healthy pregnancy on Lovenox (daughter is now 18 months) and I am currently 12 weeks pregnant and on Lovenox again. The shots aren't fun but are totally worth it :) good luck to you!

Answer

I only have Factor V Leiden and am 22 weeks and have not had to take anything yet. I will be going to a specialist though on Feb.12th to see if I have to take aspirin or blood thinners throughout the rest of my pregnancy. Also have to see if I will be allowed to deliver in my town or if I have to deliver in the city. I have never had any blood clotting problems though. Make sure to talk to your doctor about it and see what they suggest is the best option for you.

Answer

Meee! It's not so bad. I'm 16 weeks now with our little miracle baby. I have PCOS (that caused infertility problems) and PAI-1 (blood disorder). So after a long journey to get pregnant, we lost our little one right before I started lovenox. I found out the day I was supposed to start the shots. So this time I started lovenox sooner, and everything has been going smoothly. She is a happy, healthy baby girl :). I started them at 5 weeks and I will stay on them until 6 weeks post partum. I also take aspirin. I started it while trying to conceive.

Answer

Hi, I know this is an old post, but I found out I have hetero factor v and hetero mthfr (A1298C) and I wanted to see if any of you had trouble conceiving. I realize we are at higher risk during pregnancy, but didn't know if it could be the cause of not being able to get pregnant as well. We have been trying for 10 mos, 3 failed rounds of clomid and re wants to do Femera and iui next. Any info is appreciated!

Answer

I am like you!! MTHFR homozygous AND FVL homozygous. Im 6w2d, taking 81mg aspirin every day. I will see an hematologist wednesday and I think I will have lovenox/heparin injections. So stressful, I hope my baby is okay! Let me know what happens to you!! Of what I heard, those mutations are not a cause of infertility if professionals know about it and if you take care of it. GL TTC! :)

TTC with MTHFR and Factor V Leiden !?!

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