So finally my doctor said I can split up my dose of 2000mg of metformin 2 at breakfast and w at dinner instead of all 4 at once which tmi gives me explosive diarrhea(sorry) anyone else taking it as a split up dosage and be able to handle it better? I take it for PCOS by the way and it sucks when I need it to get pregnant but makes me so sick I can't even have sex cause I'm afraid or getting sick during the deed!!!!!