Ughhh heartburn!

Is it just me or is there anyone else out there suffering from horrible heartburn every minute of the day and night? I'm literally never without it. It's so bad I throw up from it and Listerine has became my new best friend that I never leave home without! I've tried the medicine my Ob prescribed, vinegar remedies, even baking soda and water shots do not help. I only drink water all day every 30 minutes an 8oz glass goes down and nothing works... Help!?: please?