About to F*** lose my mind!!!

Sorry for the language, but I'm about to F*** lose it! I have a 2 yo. Toddler girl and her 16 months old sister. And expecting our last baby 26 th of August (36 weeks pregnant). My 2 yo. Is a mix of raccoon/pester/destroyer! I'm so sick of her, she destroys everything! My shoes, my new art pencils, the baby new things, the bed, furniture, anything you can think of has been at least chewed of destroyed by markers/ sharpies! I have to throw away a chair because it was all Sharpied. I've put gates, baby locks, everything that is available on the market, door knobs you name it. She gets through everything and climb all over the place like a monkey. I'm so tired and sick of it, I'm constantly cleaning/punishing her and it doesn't seem to stop her. She keeps destroying my things. And I'm about to have an emotional break down. She chewed and broke my newly bought art pens and chewed my leather boots. She's not teething tho, all her teeth are in. I had to throw so many things away! From clothes, to furniture, pens, baby stuff. I cannot deal with her anymore.