sick or something else

Nicole
3 week old has seemed very uncomfortable for the past few days. He will not lay in his bassinet and sleep on his own where as he used to prior to these three days. He'd take a four our nap once a day and now he won't sleep for 10 minutes on his own. His appetite is good and he's peeing and popping well. Should I be worried? He just seems uncomfortable. He sleeps well if I'm holding him only.