Uncomfortable vagina

So I've had a good amount of sex lately and not all from the same partner, I use condoms with all but one of the guys I have sex with because I trust him and I have the IUD. In the past couple days, my vagina has felt different. It feels a little irritated on the outside and right at the beginning of the hole. It's kind of itchy and I think there's little pimples on the space between the vaginal hole and butthole. Addionally, my lips down there feel different, can't really explain that though. Is this something I should worry about?