When to test

My husband and I have been TTC for a little under a year. In February we took a break from stressing over it. Fast forward to this week. I am 5 days late for my AF. My breasts have been sore all week - more so than usual (like laying on them is a no go). And I had some lite cramping on Sunday - but nothing now. I tested Monday and it was negative. Do I test again?