I am at 32 weeks, 2nd pregnancy... It seems to be at night or first thing in the morning the most, whenever I am trying to get rest. And the spasms stay for quite awhile... I try to walk them out, massage them, get into a hot shower... nothing seems to help. I have to sometimes just let them pass and it is really painful even my toes start locking up and I can feel the muscles spasms. Its primarily in the right leg also, but has happened in the left. I don't remember this at all with my 1st pregnancy.