Anyone trying to get pregnant after being on the depo shot for a long period of time? My husband and I have been trying since January. I had been on the depo shot for 10 years, took my last 3 month dose in September 2015. And have been trying since then. My hormones have been haywire since I came off the shot. Always thought I would be a fertile Myrtle, so I'm a bit discouraged and am feeling like maybe its because I stayed on BC for so long, or maybe my age.. any advice? Thanks