Has anyone else ever experienced this?

I have been experiencing very tender breasts and some nausea this past week. My next period is 17 days away and I have had an IUD since August. My partner and I do not use protection. I have already taken a pregnancy test and it was negative. Is it normal to just feel out of wack for no reason? I mean I am experiencing flu like symptoms and went to the doctor today. I was prescribed medicine for it. But the tender breasts makes no sense to me. I'm beginning to worry and stress.