Ladies who suffer from migraines before and during pregnancy: what do you take to manage them? I used to be on Topamax as  a daily preventative. Not only is that drug unsafe during pregnancy but I don't want to be on a daily medication (or honestly any during pregnancy). I just want something to take PRN to make it stop. I just finally got rid of a two day migraine after breaking down and taking Excerine Migraine -.-