Can heartburn or indigestion linger in one spot?

Meagan B Tutor
I have been taking tums and zantac but not together. It seems like whatever I take, it's still there. It's horrible when I lay day and I don't get much sleep at night because of it but I do prop up on pillows but it still remain the same. I've been drinking water and maybe some Pepsi to see if it will help but it doesn't. I'm 32 weeks pregnant! I hate heartburn and indigestion!