TTC & My Granny

So I'm the 1st and oldest out of 10 grandkids. I'm 26, got my Bachelors degree, hubby and I have been married for almost 3 years, been together for 7, and naturally we chose to start trying to expand our family. My granny has always said "now shelby, I don't want to be an old great gma so you need to give me great grand babies soon" ever since my husband and I started dating. She's only 70, so I consider her being young for having a 26 yr old grand daughter. I've got some health issues on top of being told I'll have trouble trying to conceive bc of endo, PCOS, a cyst that took half my ovary, and more. Hubby and I have been TTC for a year and a few months, I'm on metformin, and I start seeing a fertility specialist next month. We were keeping our journey a secret for a while but recently told our families we're trying and that it's not going very well bc I wanted the support. My brother Brody on the other hand is 20, has a fiancé he's only known for a year, has no plan to better his future education or job wise, and lives pay check to pay check. So, just recently I was with my granny and my future SIL and my granny says to me, "how's it going, ru pregnant? No?? Well it took me a year when I was 18 to have your mom, but then again your papaw was overseas for 10 months. Do you think you can even get pregnant? I'm getting old, I want a great grandchild" So on and so forth. Just non stop asking me questions. I patiently answer them like I do every time I call her or see her. She then turns to my future SIL and says "katie, I still think you and Brody (my little brother) will give me my first grandchild." LIKE WTF BRENDA?!!!! I was so upset I looked at my mom and said "this is why I don't tell you all anything bc of this shit that is constantly said to my face or around me" I looked at my granny and SIL and said "if they do, good for them. It'll give you everything you want in life. But seeing as how they can barely support themselves or each other for that matter I pray they wait until they're more mature and stable in their lives!!!!!" I'm not knocking anyone who has kids early or isn't married or anything, but I just feel like it's so shitty of her to just give up on me for giving her a great grandchild. I'm at the point where idk what to say to her when she says that stuff to me. It's so insensitive and just kind of cruel to discount me when all I want is some support. If I would've known about her being this way, I would have never told her. DONT YOU THINK I WANT A BABY TOO BEANIE?!! Not being told you think my little brother is gonna knock up his fiancé first. What can I do/say to her to not be a bitch but to get my point across?