Does anyone here have BPD and take an anti depressant? If so which one and we're there many side effects? Recently I have been struggling with my BPD and major depression a bit recently. The last time I was on antidepressants was 10 years ago. My Zoloft stopped working and the cymbolta they prescribed was astronomically expensive. Because of my past history of being over prescribed medication from doctors at a young age, I'm somewhat on the fence about going back on them. I felt my best on Zoloft and I want that feeling again.