The study with cough syrup

Article title: Improvement of cervical factor with guaifenesin

40 women took 200 mg of guaifenesin three times a day starting at CD5 until temp rise. They all had a history of at least 10 months of infertility. 23 got pregnant. These are the results:

"Twenty-three of 40 patients showed marked improvement in postcoital tests following treatment, while 7 showed slight improvement. In every case the improvement was associated with

improvement in the mucus quality (improved spinnbarkeit and decreased cellularity).

Fifteen pregnancies in 23 couples (65.2%) occurred in the group showing marked improvements in postcoital tests after guaifenesin therapy. One patient with only a mild improvement in sperm survival achieved a pregnancy. In ten patients with hostile mucus as the only detectable cause of the infertility, eight became pregnant in an average of 2.4 months. In the remaining eight patients achieving pregnancies, where other fertility problems coexisted, there was an average of 5.6 months of treatment with guaifenesin. One patient, despite a marked improvement in sperm survival and no other apparent cause for infertility, did not achieve a pregnancy after 6 months of guaifenesin therapy. Only one of seven patients showing a slight improvement in sperm survival achieved pregnancy. The failure of eight patients to achieve pregnancies despite marked improvement in sperm survival can be accounted for by other associated fertility problems."