New mommy with a 6 day old

My daughter is 6 days old and the last few days has been way more fussy than usual. Wants to be held all the time and screams every time you put her down. I’ve been keeping track of what her diaper changes look like, but she’s started to spit up quite a bit. Today alone she’s spit up 5 times, usually after I feed her. It hasn’t been small amounts of spit up for the most part. She doesn’t have a temperature at all, but you can tell she doesn’t feel good. We have an appointment with her doctor for a follow up on Wednesday, but don’t feel like I should wait till then to take her somewhere? What are your thoughts? Am I being just a paranoid new first time mom or does it sound like something she needs to be seen sooner than later for?